It is a great pleasure to write the foreword to Forensic DNA Profiling: A Practical Guide to Assigning Likelihood Ratios, the excellent new book by the gifted researchers and teachers Jo-Anne Bright and Mike Coble. Jo-Anne Bright, from the government forensic service, ESR, in New Zealand, has a casework and research career that spans the modern transition to probabilistic genotyping. This is a transition in which she has been pivotal, with contributions to the underlying science and the development of the widely used software STRmix and a broad international teaching and support contribution. Mike Coble brings to the book the product of an outstanding career in US government organizations, most recently NIST. He is now associate director of the Center for Human Identification at the University of North Texas Health Science Center. Coble’s career also spans the transition to probabilistic genotyping. In the period preceding probabilistic genotyping (PG), he worked extensively with the US and international community, making seminal contributions to the improvement of interpretation methods and standards. His recommendations for best practice are a significant part of the motivation for the current movement to PG.