The Second International ICST Conference on Digital Forensics and Cyber Crime (ICDF2C 2010) was hosted in Abu Dhabi, United Arab Emirates, during October 4–6, 2010. The conference was attended by over 100 international participants including academics, senior government officials from the UAE, and corporate attendees. ICDF2C 2010 attracted significant media attention and was featured in prestigious media outlets such as The National, Gulf News, Al Bayan, Khaleej Times and Abu Dhabi TV. The conference program showcased credible, peer-reviewed academic research paper presentations, industry speakers, and two tutorials. Keynote presenters of this year’s conference were exceptional experts of the field. Paul Kurtz, a world renowned cyber security expert, former Assistant to the President of the United States and Senior Director for Critical Infrastructure Protection in the White House Homeland Security Council, presented on the first day. Marcus Rogers, research scholar, professor, and a fellow of CERIAS, delivered his keynote address on the second day. The third day tutorials addressed special topics in digital forensics. The session presented by respected scholar Nasir Memon from NYU-Poly focused on the latest advancements in digital image forensics. The second tutorial led by Bhadran V.K., Director of the Resource Centre for Cyber Forensics in India, concentrated on issues of network forensics.